Use a vocal remover or stem-separation app
Upload the song to an online vocal isolation tool
Open the track in a digital audio workstation with stem separation
Use AI-based source separation software to extract vocals
Apply phase cancellation if you have instrumental and full versions
Use an equalizer to reduce midrange frequencies where vocals often sit
Use a center-channel remover plugin
Export the instrumental track after processing
Check the result for leftover vocal artifacts
Save the cleaned instrumental in your preferred format