Fly into Key West International Airport (EYW)
Fly into Miami International Airport (MIA) or Fort Lauderdale-Hollywood International Airport (FLL), then drive to Key West
Drive from mainland Florida via the Overseas Highway (U.S. 1)
Take a bus or shuttle from Miami, Fort Lauderdale, or other Florida cities
Take a ferry or private boat, if available
Use a rideshare or taxi for part of the trip, then continue by road or air
Rent a car in Florida and drive the Florida Keys to Key West