Determine the balanced chemical equation
Identify the stoichiometric mole ratio between titrant and analyte
Calculate the moles of one reactant at equivalence using the mole ratio
Use concentration and volume to find moles: moles = molarity × volume
Set moles of acid equal to moles of base according to the balanced equation
Solve for the unknown volume, concentration, or amount at the equivalence point
For acid-base titrations, use the point where moles of H+ equal moles of OH−
For polyprotic acids or bases, apply the stoichiometric ratio for each equivalence point
If using a titration curve, locate the inflection point where the pH changes most rapidly
If using a derivative curve, identify the maximum in the first derivative of pH versus volume