Strip the bedding and wash it separately
Vacuum the mattress surface
Blot fresh stains with a clean dry cloth
Mix mild dish soap with cold water
Dampen a cloth with the solution
Blot the stain gently
Avoid soaking the mattress
Blot with a clean damp cloth to remove soap residue
Sprinkle baking soda over the area
Let it sit for several hours
Vacuum up the baking soda
For sweat or odor stains, use equal parts water and white vinegar
For blood stains, use cold water only
For urine stains, blot first, then use an enzyme cleaner
For food or drink stains, treat as soon as possible
Repeat treatment if needed
Let the mattress dry completely before remaking the bed
Use a fan or open windows to speed drying
Protect the mattress with a waterproof cover