How to Diagnose Ankylosing Spondylitis?

Review symptoms and history of inflammatory back pain

Check for morning stiffness lasting more than 30 minutes

Assess improvement with exercise and worsening with rest

Ask about alternating buttock pain

Examine for reduced spinal mobility and chest expansion

Look for peripheral arthritis, enthesitis, or dactylitis

Check for eye inflammation, psoriasis, or inflammatory bowel disease

Order blood tests for inflammation markers such as ESR and CRP

Test for HLA-B27

Obtain imaging of the sacroiliac joints and spine

Use X-rays to look for sacroiliitis and structural changes

Use MRI to detect early inflammation if X-rays are normal

Apply clinical criteria and imaging findings together

Refer to a rheumatologist for confirmation

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