Soak your hands in warm water for 10 to 15 minutes
Gently rub the calluses with a pumice stone, washcloth, or hand file
Apply a thick moisturizer or hand cream after soaking and exfoliating
Use creams with urea, salicylic acid, or lactic acid if appropriate
Repeat gentle exfoliation regularly, not aggressively
Wear gloves when lifting weights, using tools, or doing repetitive work
Reduce friction and pressure on the affected areas
Keep hands moisturized daily
Avoid cutting, shaving, or picking at calluses
See a doctor or dermatologist if the calluses are painful, cracked, bleeding, or infected