Use a Pill of Black Heart? No
Use a Pill of Health Up? No
Use a Pill of Amnesia? No
Use a Pill of Curse of the Maze? No
Use a Pill of I Can See Forever? No
Use a Pill of ??? No
Use a Pill of Luck Up? No
Use a Pill of Range Up? No
Use a Pill of Speed Up? No
Use a Pill of Tears Up? No
Use a Pill of Balls of Steel? No
Use a Pill of Full Health? No
Use a Pill of Bad Gas? No
Use a Pill of Paralysis? No
Use a Pill of Pretty Fly? No
Use a Pill of Explosive Diarrhea? No
Use a Pill of Telepills? No
Use a Pill of Hematemesis? No
Use a Pill of Puberty? No
Use a Pill of Addicted!? No
Use a Pill of Question Mark? No
Use a Pill of One Makes You Larger? No
Use a Pill of One Makes You Smaller? No
Use a Pill of Infested? No
Use a Pill of Re-Lax? No
Use a Pill of Retro Vision? No
Use a Pill of Friends Till The End? No
Use a Pill of Gulp!? No
Use a Pill of Horf? No
Use a Pill of Vurp? No
Use a Pill of Bad Trip? No
Use a Pill of Health Down? No
Use a Pill of Power Pill? No
Use a Pill of Tears Down? No
Use a Pill of Luck Down? No
Use a Pill of Range Down? No
Use a Pill of Speed Down? No
Use a Pill of Amnesia? No
Use a Pill of I Found Pills? No
Use a Pill of ??? No
Use a Pill of Experiment? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use a Pill of ??? No
Use The Sun? No
Use The Stars? No
Use The World? No
Use The Fool? No
Use The Hermit? No
Use The Magician? No
Use The High Priestess? No
Use The Empress? No
Use The Emperor? No
Use The Hierophant? No
Use The Lovers? No
Use The Chariot? No
Use Justice? No
Use The Hermit? No
Use Temperance? No
Use The Devil? No
Use The Tower? No
Use The Stars? No
Use The Moon? No
Use The Sun? No
Use Judgment? No
Use The Hanged Man? No
Use Death? No
Use The Wheel of Fortune? No
Use Strength? No
Use The Hermit? No
Use The World? No
Use The Fool? No
Use The Sun? No
Use The Moon? No
Use The Stars? No
Use The World? No
Use a card that removes curses? No
Use a Curse Room? No
Use a Sacrifice Room? No
Use a Devil Deal? No
Use a Planetarium? No
Use a Shop item? No
Use a Library item? No
Use a Treasure Room item? No
Use a Boss Room item? No
Use a Secret Room item? No
Use a Super Secret Room item? No
Use a Crawl Space item? No
Use a Dice Room? No
Use a challenge room? No
Use a boss trap room? No
Use a hidden room? No
Use a tinted rock? No
Use a golden chest? No
Use a red chest? No
Use a stone chest? No
Use a locked chest? No
Use a bomb? No
Use a key? No
Use a heart? No
Use a trinket? No
Use a familiar? No
Use a passive item? No
Use an active item? No
Use a rune? No
Use a pill? No
Use a card? No
Use a soul heart? No
Use a black heart? No
Use a bone heart? No
Use a golden heart? No
Use a rotten heart? No
Use a eternal heart? No
Use a broken heart? No
Use a curse-clearing item? No
There is no direct way to remove floor curses once applied
Curses usually last until the next floor
The Sun card reveals the map but does not remove curses
The World card reveals the map but does not remove curses
Black Candle prevents curses from appearing
Goat Head does not remove curses
The Bible does not remove curses
Plan accordingly for the rest of the floor