Persistent weight gain, especially around the abdomen, face, and upper back
Rounded or puffy face
Thin skin that bruises easily
Purple or pink stretch marks, especially on the abdomen, thighs, or arms
Muscle weakness, especially in the arms and legs
Fatigue or low energy
High blood pressure
High blood sugar
Increased thirst or urination
Trouble sleeping
Anxiety, irritability, or mood changes
Headaches
Irregular menstrual periods
Decreased sex drive
Acne
Slow wound healing
Frequent infections
Bone loss or fractures
Increased appetite
Facial redness
Excess hair growth on the face or body
If symptoms are persistent or severe, a medical test is needed to confirm high cortisol