Right-click the desktop item
Select Delete to remove the shortcut or file from the desktop
If you only want to hide icons, right-click the desktop
Go to View
Uncheck Show desktop icons
Move files from the Desktop folder to another folder
Open File Explorer
Go to This PC
Open the Desktop folder
Cut and paste items to a different location
Delete only shortcuts, not the original programs
Use Unpin from taskbar or Start if the item is pinned there
Empty the Recycle Bin if needed
Do not delete system files or Windows folders