Install Python from python.org or your package manager
Open a terminal or command prompt
Navigate to the folder containing the Python file
Run `python filename.py`
If needed, run `python3 filename.py`
On Windows, you can also use `py filename.py`
If the file is in another directory, use the full path like `python /path/to/filename.py`
If you are using a virtual environment, activate it first
If the script requires arguments, add them after the filename like `python filename.py arg1 arg2`