Persistent bone pain that gets worse over time
Pain that is worse at night or at rest
Swelling or a lump near a bone
A bone that breaks more easily than expected
Limited movement in a joint near the affected bone
Unexplained weight loss
Fatigue
Fever without a clear cause
Bone tenderness
Limping or trouble walking
Numbness or weakness if a tumor presses on nerves
See a doctor promptly if these symptoms last more than a few weeks or keep getting worse