Choose Bacteria for the easiest first win
Start in China, India, or Saudi Arabia
Evolve Transmission: Air 1, Water 1, then Air 2 and Water 2
Evolve Livestock and Birds if needed for spread
Keep symptoms unspent early
Evolve Drug Resistance 1 and 2
Evolve Heat Resistance or Cold Resistance based on starting region
Evolve Genetic Hardening if cure starts early
Save DNA points until most countries are infected
Infect isolated countries before going lethal
Use Devolve all lethal symptoms if cure is low and spread is still needed
When every country is infected, evolve lethal symptoms fast
Prioritize Necrosis, Total Organ Failure, and Coma
Use Genetic Reshuffle if the cure gets too high
Use abilities that slow cure when available
Kill the last healthy countries before cure completes
For Virus, devolve random symptoms that appear
For Fungus, use Spore Burst to reach islands and remote countries
For Parasite, focus on transmission and cure resistance
For Nano-Virus, slow the cure immediately
For Neurax Worm, use worm-specific spread abilities early
For Necroa Virus, build zombies and spread before attacking
For Simian Flu, spread through ape colonies first
For Prion, build cure resistance early
For every plague, avoid killing too early
For every plague, monitor island nations closely
For every plague, spread before you become deadly
For every plague, adapt strategy to the plague type and scenario