Open the pause menu
Go to the Game tab
Select Save Game
Choose an available save slot
Confirm to save
Use your safehouse bed
Walk to the bed
Follow the on-screen prompt to sleep and save
Use quick save on supported versions
Open the pause menu
Select Quick Save if available
Make sure autosave is enabled
Open Settings
Go to Game settings
Turn Autosave on
Save before quitting
Confirm the save icon appears
Exit the game after saving completes