Strip the bed of all sheets, pillowcases, blankets, and mattress protectors
Wash bedding according to the care labels
Vacuum the mattress thoroughly, including seams and edges
Spot clean stains on the mattress with a mild cleaner
Let the mattress air dry completely
Sprinkle baking soda on the mattress and vacuum it off after a few hours
Clean the bed frame with a damp cloth and mild soap
Dust and wipe the headboard, footboard, and side rails
Rotate or flip the mattress if recommended by the manufacturer
Put on clean bedding and mattress protector
Wash pillows and blankets as needed
Air out the room to reduce moisture and odors