Use the latest version of Lightroom Classic or Lightroom with the newest AI Denoise improvements
Apply Denoise only to high-ISO images that actually need it
Start with a lower Denoise amount and increase only if necessary
Crop and straighten before denoising to reduce processing load
Reduce noise in batches by selecting multiple similar images and syncing settings
Close other heavy applications while denoising
Use a computer with a faster GPU and more VRAM
Enable GPU acceleration in Lightroom preferences
Keep Lightroom updated for performance improvements
Store catalogs and photos on an SSD instead of an HDD
Increase available RAM if your system is low on memory
Denoise on smaller files when possible
Avoid unnecessary edits before running Denoise
Use Smart Previews for smoother editing on large RAW files
Keep your graphics drivers up to date
Restart Lightroom if performance slows during long editing sessions
Export after denoising instead of repeatedly reapplying the effect
Use the minimal amount of sharpening and masking needed after denoising
Reduce background sync and cloud activity while working
Work on one image at a time for the fastest individual processing
Remove old previews and optimize the catalog regularly