Keep her indoors
Provide a quiet, comfortable space
Give extra attention and gentle petting if she wants it
Use interactive play to distract her
Keep her away from intact male cats
Close windows and doors securely
Use a warm blanket or heating pad on low, if she likes it
Offer regular meals and fresh water
Clean the litter box often
Use pheromone diffusers designed for cats
Contact a veterinarian about spaying
Ask a veterinarian if short-term medication is appropriate