Keep skin clean and dry
Apply anti-chafing balm, petroleum jelly, or zinc oxide
Wear moisture-wicking, breathable fabrics
Choose properly fitting clothing
Use seamless or flat-seam underwear
Change out of sweaty clothes promptly
Use powders designed to reduce moisture
Apply bandages or protective dressings to high-friction areas
Stay hydrated
Trim body hair if it increases friction
Use lubricants for repetitive activity
Reduce repetitive rubbing when possible
Maintain a healthy weight if excess skin friction is a factor
Treat any rash or broken skin promptly
Seek medical care if chafing is severe, infected, or persistent