Choose a growing method: grow kit, sawdust block, or supplemented hardwood substrate
Use clean, fresh Lion’s Mane grain spawn from a reliable source
Prepare the substrate with hardwood sawdust and supplements if using a custom setup
Sterilize or pasteurize the substrate as required
Inoculate the cooled substrate with spawn in a clean environment
Seal the bag or container with filter patches or proper gas exchange
Incubate at about 65–75°F until fully colonized
Keep the colonized block in indirect light with high humidity
Cut slits or open the bag where mushrooms will fruit
Maintain humidity around 85–95%
Provide fresh air exchange to prevent malformed growth
Keep temperature around 60–70°F during fruiting
Mist lightly as needed to keep the surface moist without soaking it
Harvest when the spines are well formed and before yellowing
Cut the mushroom cleanly at the base
Store harvested mushrooms in the refrigerator and use soon
Clean and sanitize all tools and growing areas between batches