Spay or neuter the cat
Clean sprayed areas thoroughly with an enzymatic cleaner
Identify and remove stressors
Provide enough litter boxes
Keep litter boxes clean
Use unscented, low-dust litter
Place litter boxes in quiet, accessible locations
Reduce conflicts between cats
Block access to previously sprayed spots
Use pheromone diffusers
Maintain a consistent routine
Give the cat enough play and enrichment
Check for urinary or medical problems with a veterinarian
Limit outdoor cat visibility through windows
Use deterrents on marked areas after cleaning
Reintroduce cats slowly after household changes