Wash hands with lukewarm water and a gentle, fragrance-free soap
Pat hands dry instead of rubbing
Apply a thick, fragrance-free moisturizer after washing
Use cold compresses on the palms for short periods
Avoid hot water, harsh soaps, and sanitizers with strong alcohol content
Wear gloves when using cleaning products or handling irritants
Avoid scratching the palms
Use over-the-counter anti-itch cream if appropriate
Take an oral antihistamine if itching is related to allergies and it is safe for you
Keep nails short to reduce skin damage from scratching
Identify and avoid possible triggers such as new lotions, detergents, or foods
Stay hydrated
Seek medical care if itching is severe, persistent, or accompanied by rash, swelling, pain, or blisters