Do not stop Prozac (fluoxetine) abruptly without your prescriber’s guidance
Ask your prescriber for a taper plan tailored to your symptoms, dose history, and diagnosis
A common taper from 20 mg may be:
20 mg daily for 1–2 weeks
10 mg daily for 1–2 weeks
10 mg every other day for 1–2 weeks only if specifically directed by your prescriber
Stop only when your prescriber says it is appropriate
Some people may need a slower taper
Some people may be able to stop directly from 20 mg because Prozac has a long half-life
Use the liquid form if a smaller dose reduction is needed
Contact your prescriber if you get withdrawal symptoms, mood changes, anxiety, dizziness, nausea, sleep problems, or suicidal thoughts
Do not change the taper if you are pregnant, breastfeeding, or taking other psychiatric medicines without medical advice
Seek urgent help if you have severe depression, suicidal thoughts, or signs of mania