A new spot, mole, or growth that appears and does not go away
A mole or spot that changes in size, shape, color, or texture
An asymmetrical mole
Irregular, blurred, or jagged borders on a mole
More than one color in a mole or spot
A mole or spot larger than about 6 mm, especially if changing
A sore that does not heal
A spot that bleeds, crusts, or scabs repeatedly
A spot that itches, hurts, or becomes tender
A shiny, pearly, pink, red, or translucent bump
A firm red nodule
A flat, scaly, rough, or crusted patch
A dark streak under a fingernail or toenail
A mole or spot that looks different from your other moles
A mole or spot that keeps growing
A mole or spot with uneven color or multiple shades
Any skin change that is new, persistent, or worsening
A dermatologist evaluation if you notice any of these signs