Swelling in the feet, ankles, hands, or face
Changes in how often you urinate
Foamy or bubbly urine
Blood in the urine
Pain or burning when urinating
Pain in the lower back or side
High blood pressure
Fatigue or weakness
Loss of appetite
Nausea or vomiting
Trouble sleeping
Muscle cramps
Itchy skin
Shortness of breath
Trouble concentrating
Unexplained weight gain
Dark, cloudy, or unusually colored urine
Frequent nighttime urination
A persistent metallic taste in the mouth
If symptoms are present, seek medical evaluation and kidney function testing