Severe lethargy or unresponsiveness
Refusing food and water
Difficulty breathing or very slow, irregular breathing
Extreme weakness or inability to stand
Collapse or loss of consciousness
Cold body temperature, especially ears, paws, or limbs
Pale, gray, or blue gums
Incontinence or loss of bladder and bowel control
Persistent vomiting or diarrhea
Seizures or uncontrolled twitching
Hiding constantly and avoiding all contact
No interest in surroundings or favorite activities
Rapid decline over hours or days
Signs of severe pain, such as crying, panting, or tense posture
If these signs are present, seek urgent veterinary care immediately