Invoke the 25th Amendment (if applicable) to remove the President via removal for incapacity and/or transfer of power
Use the 25th Amendment to remove the Vice President and designate a new Vice President, then proceed with incapacity procedures for the President
Seek resignation by political pressure, negotiation, or voluntary departure
Pursue removal through constitutional succession mechanisms if the President dies, resigns, is removed under the 25th Amendment, or is otherwise unable to serve under constitutional terms
Initiate impeachment proceedings if the goal is removal by the constitution’s specified mechanism (impeachment is the only constitutionally explicit removal process)
Attempt to change the officeholder through elections at the end of the term or via an election-driven replacement
Seek a court ruling or legal determination about eligibility, incapacity, or unlawfulness of actions consistent with existing constitutional and statutory law