Prescription options: dapoxetine, SSRIs such as sertraline, paroxetine, fluoxetine, clomipramine
Topical anesthetics: lidocaine spray, lidocaine-prilocaine cream
PDE5 inhibitors if erectile dysfunction is also present: sildenafil, tadalafil, vardenafil
Over-the-counter supplements: limited evidence; consult a clinician before use
Avoid mixing with alcohol or recreational drugs
Check for drug interactions before taking any pill
Use only as directed by a healthcare professional
Seek medical advice if premature ejaculation is persistent or sudden
Do not use prescription pills without a prescription
Stop and get urgent help for chest pain, severe dizziness, fainting, or allergic reaction