Keep the corners of the mouth clean and dry
Apply a barrier ointment such as petroleum jelly or zinc oxide several times a day
Use an antifungal cream if yeast is the cause
Use an antibiotic ointment if a bacterial infection is the cause
Apply a mild hydrocortisone cream only if recommended by a clinician
Avoid licking, biting, or picking at the corners of the mouth
Use a lip balm or moisturizer regularly
Switch to a gentle toothpaste and avoid irritating mouth products
Address drooling, ill-fitting dentures, or braces if present
Treat any iron, vitamin B12, folate, or zinc deficiency
Keep hydrated
See a healthcare professional if it lasts more than 1 to 2 weeks, keeps returning, or is severe