Vacuum them up with a hose attachment and empty the vacuum bag or canister outdoors immediately
Seal entry points with caulk, weatherstripping, and screens to prevent more from getting inside
Use sticky traps near windows, doors, and other entry areas
Apply a residual insecticide labeled for indoor use to cracks, crevices, and exterior entry points according to the label
Treat exterior walls, soffits, eaves, and window frames with a perimeter insecticide labeled for ladybugs
Reduce indoor attractants by keeping lights off near windows at night and closing curtains
Remove them manually with a damp cloth or by sweeping them into a container
Call a licensed pest control professional for large infestations