Gallstones form when bile contains too much cholesterol, too much bilirubin, or too little bile salts
Risk increases with obesity
Risk increases with rapid weight loss
Risk increases with pregnancy
Risk increases with female sex
Risk increases with age
Risk increases with family history
Risk increases with a high-fat, low-fiber diet
Risk increases with certain medical conditions such as diabetes, liver disease, or Crohn’s disease
Risk increases with some medications such as estrogen therapy or certain cholesterol-lowering drugs
Risk increases with not eating for long periods or frequent fasting