Open Windows Security
Go to Virus & threat protection
Select Manage settings
Turn off Real-time protection
Go to App & browser control
Turn off Reputation-based protection settings
Open Group Policy Editor
Navigate to Computer Configuration > Administrative Templates > Windows Components > Microsoft Defender Antivirus
Open Turn off Microsoft Defender Antivirus
Set it to Enabled
Restart the computer
Open Registry Editor
Navigate to HKEY_LOCAL_MACHINESOFTWAREPoliciesMicrosoftWindows Defender
Create or set DisableAntiSpyware to 1
Restart the computer
Use a third-party antivirus if you want Defender to stay disabled
Re-enable protection later by reversing the changes