New or changing mole, spot, or growth
Asymmetry in shape
Irregular or blurred borders
Uneven color or multiple colors
Diameter larger than 6 mm
Rapid growth or noticeable change over time
Itching, tenderness, pain, or bleeding
Scab that does not heal
Sore that keeps reopening
Pearly, shiny, or waxy bump
Firm red nodule
Flat lesion with a scaly or crusted surface
Dark streak under a nail
Spot that looks different from other spots on your skin
Any lesion that changes in size, shape, color, or texture