Change diapers often
Clean the area gently with warm water
Pat the skin dry; do not rub
Give diaper-free time when possible
Apply a thick layer of zinc oxide or petroleum jelly
Use fragrance-free, alcohol-free wipes or soft cloths
Avoid tight diapers and clothing
Use super-absorbent diapers
Treat any yeast or bacterial infection if suspected
Call a doctor if the rash is severe, spreading, blistering, or not improving in 2 to 3 days