Confirm the cause with repeat ferritin testing and iron studies
Check transferrin saturation, serum iron, total iron-binding capacity, and complete blood count
Evaluate for liver disease, inflammation, infection, metabolic syndrome, alcohol use, and iron overload disorders
Stop iron supplements unless specifically prescribed
Avoid multivitamins containing iron
Limit alcohol intake
Treat any underlying condition causing inflammation or liver injury
If iron overload is confirmed, use therapeutic phlebotomy as directed by a clinician
If phlebotomy is not appropriate, consider iron chelation therapy under specialist care
Reduce intake of iron-fortified foods if advised by a clinician
Avoid raw shellfish if iron overload or liver disease is present
Monitor ferritin and transferrin saturation regularly
Follow up with a primary care clinician, hematologist, or hepatologist
Seek urgent care for chest pain, shortness of breath, severe weakness, jaundice, or confusion
