Clean the area gently with mild soap and water
Leave the blister intact if it’s not broken
Protect it with a hydrocolloid blister bandage
Change the bandage daily or if it gets wet or dirty
Reduce friction with cushioned pads, moleskin, or properly fitted footwear
Keep pressure off the blister with padding, bandaging, or different shoes
If the blister is painful, consider using an ice pack (10–15 minutes) wrapped in cloth
If the blister breaks: wash with soap and water
Apply a thin layer of petroleum jelly or antibiotic ointment
Cover with a sterile nonstick gauze pad or bandage
Keep it clean and dry, and change the dressing daily (or when wet)
Seek medical care urgently if there are signs of infection (increasing redness, warmth, swelling, pus, worsening pain, red streaks, fever)
Seek medical care if the blister is large, recurrent, won’t heal, or is from a burn, chemical exposure, or an unknown cause
Avoid popping, cutting, or draining blisters at home if you can prevent it
Avoid home remedies like alcohol or hydrogen peroxide on open blisters