Keep the blister clean and dry
Wash gently with soap and water
Do not pop it if possible
Cover it with a sterile bandage or blister pad
Use a cushioned dressing to reduce friction
Avoid pressure or rubbing on the area
If it opens, clean it and apply an antibiotic ointment if appropriate
Replace the bandage daily or when wet or dirty
Wear properly fitting shoes or protective clothing
Use moleskin or padding on areas prone to rubbing
Apply a cold compress for pain or swelling
Take over-the-counter pain relief if needed
Seek medical care if it is large, very painful, infected, or keeps coming back