Strip the bedding and vacuum the mattress
Blot fresh stains with a clean dry cloth
Mix a small amount of mild dish soap with cool water
Dab the stain with the solution using a clean cloth
Blot with a dry cloth to lift moisture
Sprinkle baking soda over the area
Let the baking soda sit for several hours
Vacuum up the baking soda
For urine stains, use equal parts white vinegar and water
For blood stains, use cold water only
For sweat stains, use a baking soda paste
For odor, lightly mist with vinegar and let dry
Repeat as needed until the stain fades
Avoid soaking the mattress
Let the mattress air dry completely before remaking the bed