Talk to a doctor or urologist before using any medication
Prescription SSRIs such as dapoxetine, sertraline, paroxetine, or fluoxetine
Topical anesthetic sprays or creams containing lidocaine or prilocaine
PDE5 inhibitors such as sildenafil, tadalafil, or vardenafil if erectile dysfunction is also present
Tramadol only if specifically prescribed by a doctor
Avoid mixing medications with alcohol or recreational drugs
Use condoms or thicker condoms to reduce sensitivity
Consider timing medication as directed by a clinician
Review side effects, interactions, and contraindications with a pharmacist or doctor
Seek medical evaluation if the problem is sudden, severe, or persistent