Seek urgent medical evaluation immediately if septicemia is suspected
Check vital signs: temperature, heart rate, respiratory rate, and blood pressure
Perform a physical examination for signs of infection and organ dysfunction
Order blood cultures before starting antibiotics when possible
Obtain a complete blood count with differential
Measure serum lactate
Check basic metabolic panel and kidney function tests
Check liver function tests
Measure C-reactive protein and/or procalcitonin
Obtain arterial blood gas if breathing problems or severe illness are present
Test coagulation studies including PT, INR, and aPTT
Check blood glucose
Obtain urinalysis and urine culture if urinary infection is suspected
Obtain cultures from suspected infection sites, such as sputum, wound, or cerebrospinal fluid
Perform imaging studies such as chest X-ray, ultrasound, or CT scan to find the infection source
Monitor oxygen saturation
Repeat blood tests and cultures if symptoms worsen or infection persists