Shut down the computer
Turn off the power supply
Unplug the power cable
Press the power button for a few seconds to discharge residual power
Open the computer case
Disconnect any power cables from the GPU
Remove any screws or retention brackets securing the GPU to the case
Release the PCIe slot latch on the motherboard
Hold the GPU by its edges
Pull the GPU straight out of the PCIe slot
Place the GPU on an anti-static surface or in an anti-static bag
Close the case if needed