Preheat the oven to 300°F
Remove the membrane from the back of the ribs
Pat the ribs dry with paper towels
Season both sides with salt, black pepper, garlic powder, onion powder, and paprika
Place the ribs on a foil-lined baking sheet or in a roasting pan
Cover tightly with aluminum foil
Bake for 3 to 4 hours until tender
Remove the foil during the last 20 to 30 minutes if you want a browned exterior
Brush with barbecue sauce if desired
Increase the oven to 400°F for the final 10 to 15 minutes to caramelize the sauce
Rest the ribs for 10 to 15 minutes before serving
Slice between the bones and serve