Trim excess fat from the brisket
Season the brisket with salt, pepper, garlic powder, and paprika
Sear the brisket in a hot skillet for 2 to 3 minutes per side
Place sliced onions and garlic in the bottom of the slow cooker
Add the brisket on top of the onions
Pour in beef broth, barbecue sauce, or a mix of broth and Worcestershire sauce
Cover and cook on low for 8 to 10 hours or on high for 4 to 6 hours
Check that the brisket is fork-tender before removing it
Transfer the brisket to a cutting board and let it rest for 10 to 15 minutes
Slice the brisket against the grain
Serve with the cooking juices or strain and reduce the sauce if desired