Do not stop Wellbutrin abruptly unless your prescriber tells you to
Ask your prescriber for a taper plan before making any dose changes
Follow the exact taper schedule your prescriber gives you
If you are taking immediate-release or sustained-release Wellbutrin, your prescriber may lower the dose step by step
If you are taking extended-release Wellbutrin, your prescriber may switch you to a lower dose before stopping
Take each reduced dose for the full amount of time prescribed before the next reduction
Monitor for withdrawal symptoms such as irritability, anxiety, agitation, headache, dizziness, nausea, or sleep changes
Contact your prescriber if symptoms become severe or do not improve
Do not split, crush, or chew extended-release tablets unless your pharmacist or prescriber says it is safe
Avoid alcohol or other substances that may increase side effects during the taper
Keep a list of all medications and supplements to review with your prescriber
Seek urgent help if you have suicidal thoughts, severe mood changes, or seizure symptoms
If you miss a dose during tapering, follow your prescriber’s instructions or the medication label
Do not change the taper schedule on your own
Arrange follow-up with your prescriber to check mood and side effects during and after tapering