See a healthcare professional if you have symptoms or a recent tick bite
Get a two-step blood test
Start with an ELISA or EIA test
If the first test is positive or equivocal, get a Western blot or second-tier test
Ask about modified two-tier testing if available
Test too early only if your clinician recommends it, since antibodies may not appear right away
Consider repeat testing if the first test is negative but symptoms persist
Use PCR or other direct tests only in specific cases, such as joint fluid or spinal fluid
Do not rely on tick testing to diagnose infection in people
Do not use home tests without medical follow-up
Discuss results with a clinician experienced in Lyme disease