Ask your prescriber before tapering, especially if you have severe reflux, ulcers, Barrett’s esophagus, GI bleeding, or take NSAIDs/aspirin regularly
Reduce from daily use to every other day for 1 to 2 weeks
Then reduce to every third day for 1 to 2 weeks
Then stop if symptoms are tolerable
If needed, switch temporarily to a lower dose before reducing frequency
Use antacids as needed for breakthrough symptoms
Consider an H2 blocker such as famotidine during tapering if approved by your clinician
Avoid large meals, late-night eating, alcohol, caffeine, and trigger foods during tapering
Elevate the head of the bed if nighttime symptoms occur
Maintain a healthy weight if applicable
Stop and contact a clinician if you develop severe heartburn, vomiting, black stools, trouble swallowing, chest pain, or persistent symptoms
Do not taper on your own if omeprazole was prescribed for a bleeding ulcer or severe esophagitis unless your clinician directs it