Pat tilapia fillets dry with paper towels
Season both sides with salt, pepper, and any desired spices
Heat a skillet over medium heat
Add oil or butter to the skillet
Place tilapia fillets in the skillet
Cook for 3 to 4 minutes on the first side
Flip the fillets carefully
Cook for 2 to 3 minutes on the second side
Cook until the fish is opaque and flakes easily with a fork
Remove from skillet and serve immediately