Wash your hands before touching the blister
Clean the area gently with soap and water
Leave small, unbroken blisters intact
Avoid popping the blister
Cover it with a clean, dry bandage or blister pad
Use a cushioned dressing to reduce pressure and friction
Change the dressing daily or if it gets wet or dirty
Wear roomy, comfortable shoes and moisture-wicking socks
Keep the foot dry and reduce rubbing
If the blister opens, do not remove the skin flap
Apply an antibiotic ointment if the blister has opened and the skin is raw
Watch for signs of infection such as redness, warmth, swelling, pus, or increasing pain
Seek medical care if the blister is large, very painful, infected, caused by burns, or if you have diabetes or poor circulation