Take levothyroxine exactly as prescribed by your doctor
Take it on an empty stomach
Take it at least 30 to 60 minutes before breakfast
Take it with a full glass of water
Swallow the tablet whole unless your doctor says otherwise
Take it at the same time every day
If you take it at bedtime, take it at least 3 to 4 hours after your last meal
Do not take it with food, coffee, or milk
Do not take it at the same time as calcium, iron, antacids, or multivitamins
Separate levothyroxine from calcium or iron supplements by at least 4 hours
Follow your doctor’s instructions if you miss a dose
Do not stop taking it without medical advice
Have your thyroid levels checked as directed by your doctor