Treat the underlying cause
Control blood sugar if diabetic
Stop alcohol use
Correct vitamin deficiencies
Review and adjust medications that may cause neuropathy
Use pain-relief medicines as prescribed
Consider nerve pain medicines such as gabapentin, pregabalin, duloxetine, or amitriptyline
Use topical treatments such as lidocaine or capsaicin
Manage inflammation or autoimmune causes with appropriate treatment
Do physical therapy and regular exercise
Protect numb feet and hands from injury
Wear proper footwear
Maintain good foot care
Use assistive devices if needed
Improve sleep and stress management
Seek urgent medical care for rapid weakness, severe pain, trouble breathing, or loss of bladder or bowel control