Wash your hands
Clean the area gently with soap and water
Apply a cold compress for 10 to 15 minutes at a time
Keep the blister intact
Cover it with a clean, dry bandage if needed
Elevate the area if it is on a hand or foot
Avoid pressure or friction on the blister
Do not pop or drain it
Use over-the-counter pain relief if needed and safe for you
Seek medical care if it is very large, very painful, infected, or not improving
Seek urgent care if you have diabetes, poor circulation, or a weakened immune system