Persistent sadness, emptiness, or hopelessness
Loss of interest or pleasure in activities you used to enjoy
Low energy or constant fatigue
Changes in sleep, such as sleeping too much or too little
Changes in appetite or weight
Trouble concentrating, thinking, or making decisions
Feeling worthless, guilty, or self-critical
Slowed movements or speech, or feeling physically restless
Irritability, frustration, or agitation
Withdrawing from friends, family, or social activities
Frequent crying or feeling emotionally numb
Unexplained aches, pains, or digestive problems
Difficulty keeping up with work, school, or daily responsibilities
Thoughts of death, self-harm, or suicide
Symptoms lasting most days for at least two weeks
Symptoms causing problems in daily life